Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activatedBy |
gptkb:ADP
|
| gptkbp:alternativeName |
gptkb:GDH
GLUD |
| gptkbp:CASNumber |
9001-46-1
|
| gptkbp:catalyzes |
oxidative deamination of glutamate to α-ketoglutarate
|
| gptkbp:cofactor |
NADP+
NAD+ |
| gptkbp:discoveredBy |
gptkb:Hugo_Theorell
|
| gptkbp:discoveredIn |
1930s
|
| gptkbp:EC_number |
1.4.1.2
|
| gptkbp:foundIn |
gptkb:kidney
liver mitochondria |
| gptkbp:gene |
gptkb:GLUD2
gptkb:GLUD1 |
| gptkbp:inhibitedBy |
gptkb:ATP
gptkb:GTP |
| gptkbp:molecularWeight |
~56 kDa (per subunit)
|
| gptkbp:participatedIn |
gptkb:urea_cycle
amino acid metabolism citric acid cycle |
| gptkbp:product |
gptkb:α-ketoglutarate
gptkb:NADH ammonia NADPH |
| gptkbp:regulates |
allosteric
|
| gptkbp:structure |
hexamer
|
| gptkbp:substrate |
gptkb:L-glutamate
|
| gptkbp:UniProtID |
P00367 (human)
|
| gptkbp:bfsParent |
gptkb:glutamate_dehydrogenase
gptkb:Glutamate_dehydrogenase |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
glutamic acid dehydrogenase
|