Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activatedBy |
gptkb:ADP
leucine |
| gptkbp:alternativeName |
gptkb:GDH
gptkb:L-glutamate_dehydrogenase gptkb:glutamic_acid_dehydrogenase |
| gptkbp:catalyzes |
oxidative deamination of glutamate to α-ketoglutarate
|
| gptkbp:cofactor |
NADP+
NAD+ |
| gptkbp:EC_number |
1.4.1.2
|
| gptkbp:encodedBy |
gptkb:GLUD2
gptkb:GLUD1 |
| gptkbp:foundIn |
gptkb:kidney
brain liver mitochondria |
| https://www.w3.org/2000/01/rdf-schema#label |
Glutamate dehydrogenase
|
| gptkbp:inhibitedBy |
gptkb:GTP
|
| gptkbp:involves |
amino acid metabolism
nitrogen metabolism |
| gptkbp:presentIn |
prokaryotes
eukaryotes |
| gptkbp:product |
gptkb:α-ketoglutarate
gptkb:NADH ammonia NADPH |
| gptkbp:significance |
gptkb:hyperinsulinism-hyperammonemia_syndrome
|
| gptkbp:structure |
hexamer
|
| gptkbp:substrate |
gptkb:L-glutamate
|
| gptkbp:bfsParent |
gptkb:GDH
|
| gptkbp:bfsLayer |
7
|