glucose transporter type 4

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:ABC_transporter
gptkbp:activatedBy	gptkb:insulin
gptkbp:alsoKnownAs	gptkb:GLUT4
gptkbp:discoveredIn	1988
gptkbp:dysregulationAssociatedWith	gptkb:type_2_diabetes_mellitus insulin resistance
gptkbp:encodedBy	gptkb:SLC2A4_gene
gptkbp:expressedIn	gptkb:brown_adipose_tissue gptkb:white_adipose_tissue
gptkbp:family	gptkb:solute_carrier_family_2
gptkbp:foundIn	gptkb:adipose_tissue gptkb:skeletal_muscle cardiac muscle
gptkbp:function	facilitated glucose transport
gptkbp:involvedIn	insulin signaling pathway glucose homeostasis
gptkbp:locale	cell surface (in presence of insulin) intracellular vesicles (in absence of insulin)
gptkbp:locatedOnChromosome	chromosome 17p13
gptkbp:molecularWeight	approximately 54 kDa
gptkbp:OMIM	138190
gptkbp:PDB	4PYP
gptkbp:regulates	regulated by insulin regulated by exercise
gptkbp:species	gptkb:Mus_musculus gptkb:Homo_sapiens
gptkbp:structure	12 transmembrane domains
gptkbp:translocatesTo	gptkb:plasma_membrane
gptkbp:UniProtID	gptkb:P14672
gptkbp:bfsParent	gptkb:ENSG00000132313 gptkb:ENSG00000130203 gptkb:ENSG00000137868 gptkb:ENSG00000105401
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	glucose transporter type 4