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glucose transporter type 4
URI:
https://gptkb.org/entity/glucose_transporter_type_4
GPTKB entity
Statements (38)
Predicate
Object
gptkbp:instanceOf
gptkb:protein
ABC transporter
gptkbp:activatedBy
gptkb:insulin
gptkbp:alsoKnownAs
gptkb:GLUT4
gptkbp:discoveredIn
1988
gptkbp:dysregulationAssociatedWith
gptkb:type_2_diabetes_mellitus
insulin resistance
gptkbp:encodedBy
gptkb:SLC2A4_gene
gptkbp:expressedIn
gptkb:brown_adipose_tissue
gptkb:white_adipose_tissue
gptkbp:family
gptkb:solute_carrier_family_2
gptkbp:foundIn
gptkb:skeletal_muscle
cardiac muscle
adipose tissue
gptkbp:function
facilitated glucose transport
https://www.w3.org/2000/01/rdf-schema#label
glucose transporter type 4
gptkbp:involvedIn
insulin signaling pathway
glucose homeostasis
gptkbp:locale
cell surface (in presence of insulin)
intracellular vesicles (in absence of insulin)
gptkbp:locatedOnChromosome
chromosome 17p13
gptkbp:molecularWeight
approximately 54 kDa
gptkbp:OMIM
138190
gptkbp:PDB
4PYP
gptkbp:regulates
regulated by insulin
regulated by exercise
gptkbp:species
gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkbp:structure
12 transmembrane domains
gptkbp:translocatesTo
gptkb:plasma_membrane
gptkbp:UniProtID
gptkb:P14672
gptkbp:bfsParent
gptkb:ENSG00000132313
gptkb:ENSG00000134352
gptkb:ENSG00000165646
gptkb:ENSG00000130203
gptkb:ENSG00000137868
gptkb:ENSG00000105401
gptkbp:bfsLayer
8