extended-spectrum beta-lactamase (ESBL)
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:detects |
molecular methods
phenotypic tests |
| gptkbp:firstDescribed |
1980s
|
| gptkbp:function |
hydrolyze beta-lactam antibiotics
|
| https://www.w3.org/2000/01/rdf-schema#label |
extended-spectrum beta-lactamase (ESBL)
|
| gptkbp:inhibitedBy |
gptkb:clavulanic_acid
tazobactam |
| gptkbp:producedBy |
gptkb:Enterobacteriaceae
gptkb:Bacteria gptkb:Klebsiella_pneumoniae |
| gptkbp:proteinFamily |
gptkb:TEM
gptkb:SHV CTX-M |
| gptkbp:publicHealthConcern |
global
|
| gptkbp:resistantTo |
gptkb:cephalosporins
gptkb:aztreonam penicillins |
| gptkbp:significance |
antibiotic resistance
|
| gptkbp:spreadTo |
plasmids
|
| gptkbp:bfsParent |
gptkb:antimicrobial_resistance_gene_CTX-M
gptkb:SHV-2 |
| gptkbp:bfsLayer |
8
|