Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
antibiotic resistance gene
|
| gptkbp:detects |
PCR
DNA sequencing |
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodes |
beta-lactamase enzyme
|
| gptkbp:foundIn |
gptkb:Bacteria
gptkb:Klebsiella_pneumoniae |
| gptkbp:fullName |
Sulfhydryl Variable
|
| https://www.w3.org/2000/01/rdf-schema#label |
SHV
|
| gptkbp:inhibitedBy |
gptkb:clavulanic_acid
|
| gptkbp:mechanismOfAction |
hydrolyzes beta-lactam antibiotics
|
| gptkbp:notableVariant |
gptkb:SHV-1
gptkb:SHV-2 gptkb:SHV-5 |
| gptkbp:proteinFamily |
class A beta-lactamase
|
| gptkbp:relatedTo |
gptkb:TEM_beta-lactamase
|
| gptkbp:resistanceThreatLevel |
high
|
| gptkbp:resistantTo |
gptkb:cephalosporins
penicillins |
| gptkbp:significance |
extended-spectrum beta-lactamase (ESBL) production
|
| gptkbp:variantCount |
over 40 variants
|
| gptkbp:bfsParent |
gptkb:Shreveport_Regional_Airport
|
| gptkbp:bfsLayer |
6
|