Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
alcohol dehydrogenase
|
| gptkbp:catalyzes |
oxidation of ethanol to acetaldehyde
|
| gptkbp:cofactor |
NADP+
NAD+ |
| gptkbp:EC_number |
1.1.1.1
|
| gptkbp:firstDescribed |
1937
|
| gptkbp:foundIn |
gptkb:yeast
gptkb:Bacteria animals plants |
| gptkbp:gene |
ADH1 (in yeast)
ADH1B (in humans) |
| gptkbp:homologs_in |
many species
|
| https://www.w3.org/2000/01/rdf-schema#label |
ethanol dehydrogenase
|
| gptkbp:inhibitedBy |
gptkb:4-methylpyrazole
pyrazole |
| gptkbp:location |
cytosol
|
| gptkbp:mutationAssociatedWith |
ADH1B affects alcohol tolerance
|
| gptkbp:PDB |
gptkb:1HTB
1ADC |
| gptkbp:presentIn |
gptkb:cancer
gptkb:kidney gptkb:testis brain liver pancreas stomach intestine bacterial cytoplasm plant cytoplasm yeast cytoplasm |
| gptkbp:product |
acetaldehyde
|
| gptkbp:relatedTo |
aldehyde dehydrogenase
methanol dehydrogenase |
| gptkbp:requires |
zinc ion (Zn2+)
|
| gptkbp:role |
fermentation
alcohol metabolism detoxification of ethanol |
| gptkbp:structure |
dimeric or tetrameric protein
|
| gptkbp:substrate |
ethanol
|
| gptkbp:systematicName |
ethanol:NAD+ oxidoreductase
|
| gptkbp:type |
oxidoreductase
|
| gptkbp:used_in |
gptkb:biotechnology
clinical diagnostics biofuel production industrial fermentation alcohol breath analyzers |
| gptkbp:bfsParent |
gptkb:Alcohol_dehydrogenase
|
| gptkbp:bfsLayer |
7
|