dual specificity phosphatase 2
GPTKB entity
Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alias |
gptkb:DUSP2
gptkb:PAC-1 gptkb:phosphatase_of_activated_cells_1 |
| gptkbp:associatedWith |
inflammation
immune response |
| gptkbp:biologicalProcess |
negative regulation of cell proliferation
protein tyrosine phosphatase activity negative regulation of MAPK cascade MAP kinase phosphatase activity |
| gptkbp:encodedBy |
DUSP2 gene
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000127914
1844 |
| gptkbp:expressedIn |
hematopoietic tissues
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
dephosphorylation of phosphoserine/threonine and phosphotyrosine residues
|
| gptkbp:HGNC_ID |
3071
|
| https://www.w3.org/2000/01/rdf-schema#label |
dual specificity phosphatase 2
|
| gptkbp:inhibitedBy |
gptkb:ERK1/2
gptkb:MAPK1 gptkb:MAPK3 |
| gptkbp:locatedIn |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
2q11.2
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:regulates |
MAP kinase activity
|
| gptkbp:UniProtID |
gptkb:Q05923
|
| gptkbp:bfsParent |
gptkb:DUSP2
|
| gptkbp:bfsLayer |
7
|