drug-induced hypersensitivity syndrome
GPTKB entity
Statements (65)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:computer
|
| gptkbp:associated_with |
autoimmune diseases
HIV infection |
| gptkbp:caused_by |
medications
|
| gptkbp:complication |
gptkb:death
sepsis organ failure toxic epidermal necrolysis Stevens-Johnson syndrome |
| gptkbp:diagnosis |
blood tests
clinical evaluation skin tests |
| gptkbp:first_described_by |
gptkb:1980s
|
| https://www.w3.org/2000/01/rdf-schema#label |
drug-induced hypersensitivity syndrome
|
| gptkbp:premiered_on |
days to weeks after drug exposure
|
| gptkbp:prevention |
genetic testing
avoidance of known allergens careful medication history |
| gptkbp:related_products |
gptkb:abacavir
gptkb:methotrexate gptkb:phenytoin gptkb:trimethoprim-sulfamethoxazole gptkb:isoniazid gptkb:lamotrigine gptkb:carbamazepine gptkb:zidovudine gptkb:rifampin gptkb:chloramphenicol antibiotics antivirals antifungals contrast agents antidepressants antipsychotics opioids antimalarials anxiolytics nevirapine antiretrovirals local anesthetics macrolides non-steroidal anti-inflammatory drugs (NSAIDs) anticonvulsants cephalosporins penicillins vancomycin muscle relaxants sulfasalazine sulfonamides dapsone allopurinol oxcarbazepine quinolone antibiotics tetracyclines |
| gptkbp:risk_factor |
age
genetic predisposition female gender previous drug reactions |
| gptkbp:symptoms |
fever
rash lymphadenopathy eosinophilia |
| gptkbp:treatment |
corticosteroids
|
| gptkbp:bfsParent |
gptkb:stevens-johnson_syndrome
|
| gptkbp:bfsLayer |
6
|