Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:antibiotic
antineoplastic agent |
| gptkbp:administeredBy |
intravenous injection
|
| gptkbp:alsoKnownAs |
gptkb:actinomycin_D
|
| gptkbp:ATCCode |
L01DB01
|
| gptkbp:CASNumber |
50-76-0
|
| gptkbp:discoveredBy |
gptkb:Selman_Waksman
|
| gptkbp:discoveredIn |
1940
|
| gptkbp:hasMolecularFormula |
C62H86N12O16
|
| https://www.w3.org/2000/01/rdf-schema#label |
dactinomycin
|
| gptkbp:includedIn |
gptkb:WHO_Model_List_of_Essential_Medicines
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits DNA-dependent RNA synthesis
|
| gptkbp:pregnancyCategory |
D (US)
|
| gptkbp:producedBy |
Streptomyces parvulus
|
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:sideEffect |
nausea
vomiting hair loss bone marrow suppression mouth ulcers |
| gptkbp:usedFor |
gptkb:Wilms_tumor
gptkb:cancer gptkb:rhabdomyosarcoma gptkb:Ewing_sarcoma gestational trophoblastic neoplasia |
| gptkbp:bfsParent |
gptkb:actinomycin_D
|
| gptkbp:bfsLayer |
7
|