cytochrome P450 family 7 subfamily A member 1
GPTKB entity
Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
gptkb:CYP7A1
gptkb:cholesterol_7-alpha-monooxygenase |
| gptkbp:associatedWith |
gptkb:familial_hypercholesterolemia
gptkb:cerebrotendinous_xanthomatosis |
| gptkbp:biologicalProcess |
oxidoreductase activity
|
| gptkbp:cofactor |
hemoglobin
|
| gptkbp:EC_number |
1.14.14.23
|
| gptkbp:encodedBy |
gptkb:CYP7A1_gene
|
| gptkbp:function |
bile acid biosynthesis
cholesterol 7 alpha-hydroxylase activity |
| https://www.w3.org/2000/01/rdf-schema#label |
cytochrome P450 family 7 subfamily A member 1
|
| gptkbp:locatedIn |
gptkb:endoplasmic_reticulum
|
| gptkbp:locatedOnChromosome |
chromosome 8q11-q12
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:pathway |
primary bile acid biosynthesis
|
| gptkbp:product |
gptkb:CYP7A1
7-alpha-hydroxycholesterol |
| gptkbp:regulates |
regulated by bile acids
|
| gptkbp:substrate |
cholesterol
|
| gptkbp:tissue_specificity |
liver
|
| gptkbp:UniProtID |
gptkb:P22680
|
| gptkbp:bfsParent |
gptkb:CYP7A1
|
| gptkbp:bfsLayer |
6
|