Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
cell cycle regulator |
| gptkbp:alias |
gptkb:CCNA
cyclin-A |
| gptkbp:binds |
gptkb:CDK2
gptkb:CDK1 |
| gptkbp:degradedBy |
gptkb:ubiquitin-proteasome_pathway
|
| gptkbp:discoveredBy |
1980s
|
| gptkbp:encodedBy |
gptkb:CCNA1_gene
gptkb:CCNA2_gene |
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
regulation of cell cycle
|
| gptkbp:hasIsoform |
gptkb:cyclin_A1
gptkb:cyclin_A2 |
| https://www.w3.org/2000/01/rdf-schema#label |
cyclin A protein
|
| gptkbp:involvedIn |
gptkb:S_phase
G2/M transition |
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:molecularWeight |
~52 kDa
|
| gptkbp:overexpressedIn |
gptkb:cancer
|
| gptkbp:phosphorylates |
gptkb:CDK2
gptkb:CDK1 |
| gptkbp:regulates |
DNA replication
mitosis transcriptionally regulated |
| gptkbp:structure |
contains cyclin box domain
|
| gptkbp:bfsParent |
gptkb:CYLCA
gptkb:CYCA |
| gptkbp:bfsLayer |
7
|