Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
gptkb:MMP-13
|
| gptkbp:discoveredIn |
1994
|
| gptkbp:EC_number |
3.4.24.23
|
| gptkbp:encodedBy |
MMP13 gene
|
| gptkbp:expressedIn |
gptkb:bone
collagen synovial tissue |
| gptkbp:familyMember |
gptkb:matrix_metalloproteinases
|
| gptkbp:function |
degrades extracellular matrix proteins
involved in tissue remodeling cleaves type II collagen |
| https://www.w3.org/2000/01/rdf-schema#label |
collagenase 3
|
| gptkbp:inhibitedBy |
gptkb:tissue_inhibitors_of_metalloproteinases_(TIMPs)
|
| gptkbp:involves |
osteoarthritis
rheumatoid arthritis tumor invasion |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_11q22.3
|
| gptkbp:molecularWeight |
~60 kDa
|
| gptkbp:regulates |
cytokines
growth factors |
| gptkbp:bfsParent |
gptkb:MMP13
|
| gptkbp:bfsLayer |
7
|