Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
blood coagulation factor |
| gptkbp:activatedBy |
gptkb:factor_IX
gptkb:factor_XIIa |
| gptkbp:alternativeName |
gptkb:PTA
gptkb:plasma_thromboplastin_antecedent |
| gptkbp:clinical_test |
factor XI activity assay
|
| gptkbp:deficiencyCauses |
gptkb:hemophilia_C
|
| gptkbp:discoveredBy |
Rosenthal et al.
|
| gptkbp:discoveredIn |
1953
|
| gptkbp:EC_number |
3.4.21.27
|
| gptkbp:foundIn |
gptkb:human
gptkb:plasma |
| gptkbp:function |
initiates intrinsic pathway of blood coagulation
|
| gptkbp:gene |
F11
|
| https://www.w3.org/2000/01/rdf-schema#label |
coagulation factor XI
|
| gptkbp:inhibitedBy |
gptkb:C1-inhibitor
gptkb:antithrombin_III |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_4q35
|
| gptkbp:molecularWeight |
80 kDa
|
| gptkbp:mutationAssociatedWith |
bleeding disorder
|
| gptkbp:OMIM |
612416
|
| gptkbp:PDB |
2F83
|
| gptkbp:presentIn |
vertebrates
|
| gptkbp:producedBy |
liver
|
| gptkbp:structure |
homodimer
|
| gptkbp:UniProtID |
gptkb:P03951
|
| gptkbp:bfsParent |
gptkb:F11_gene
|
| gptkbp:bfsLayer |
7
|