Statements (88)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:bfsLayer |
6
|
| gptkbp:bfsParent |
gptkb:G._D._Searle_&_Company
|
| gptkbp:activities |
COX-2 inhibitor
|
| gptkbp:approves |
gptkb:FDA
|
| gptkbp:brand |
gptkb:Celebrex
gptkb:Celecoxib |
| gptkbp:category |
gptkb:C
|
| gptkbp:class |
COX-2 inhibitor
|
| gptkbp:clinical_trial |
COX-2 selective inhibitors study
chronic pain management study osteoarthritis treatment study rheumatoid arthritis treatment study COX-2 inhibitor studies |
| gptkbp:contraindication |
active gastrointestinal bleeding
allergy to sulfonamides history of heart disease severe liver disease severe heart disease severe kidney disease allergy to celecoxib |
| gptkbp:developed_by |
gptkb:Pfizer
|
| gptkbp:dosage_form |
gptkb:beer
100 mg suspension 400 mg 200 mg 200 mg once daily 100 mg twice daily |
| gptkbp:duration |
as needed
long-term |
| gptkbp:effective_date |
gptkb:1998
|
| gptkbp:excretion |
urine
|
| gptkbp:formulation |
gptkb:tablet
oral suspension oral solution |
| gptkbp:has_ability |
100 mg
200 mg |
| https://www.w3.org/2000/01/rdf-schema#label |
Celebrex
|
| gptkbp:ingredients |
gptkb:celecoxib
|
| gptkbp:interacts_with |
gptkb:methotrexate
gptkb:warfarin lithium diuretics |
| gptkbp:invention |
gptkb:2014
gptkb:2015 gptkb:2020 |
| gptkbp:is_available_in |
liquid form
tablet form |
| gptkbp:is_available_on |
suspension
oral capsule |
| gptkbp:is_used_for |
pain relief
arthritis treatment inflammation reduction |
| gptkbp:legal_issue |
prescription only
|
| gptkbp:lifespan |
8 to 12 hours
|
| gptkbp:manager |
oral
|
| gptkbp:manufacturer |
gptkb:Pfizer
|
| gptkbp:marketed_as |
gptkb:legislation
gptkb:Celecoxib gptkb:1998 gptkb:Australia gptkb:Japan gptkb:United_States gptkb:Native_American_tribe |
| gptkbp:metabolism |
liver
|
| gptkbp:previous_name |
gptkb:celecoxib
gptkb:battle |
| gptkbp:requires |
gptkb:theorem
|
| gptkbp:safety_features |
allergic reactions
cardiovascular risk gastrointestinal risk kidney risk liver risk |
| gptkbp:scholarships |
avoid alcohol
do not exceed recommended dosage consult doctor if pregnant report any allergic reactions monitor for signs of gastrointestinal bleeding |
| gptkbp:side_effect |
dizziness
fatigue headache nausea diarrhea rash stomach pain edema |