|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:CR
gptkb:ERp60
calregulin
CaBP3
GRP-60
HACBP
calsequestrin-like protein
|
|
gptkbp:associatedWith
|
myeloproliferative neoplasms
|
|
gptkbp:discoveredBy
|
1974
|
|
gptkbp:foundIn
|
gptkb:endoplasmic_reticulum
|
|
gptkbp:function
|
molecular chaperone
calcium-binding
|
|
gptkbp:gene
|
gptkb:CALR
|
|
gptkbp:GO_term
|
GO:0005783 (endoplasmic reticulum)
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
calreticulin
|
|
gptkbp:interactsWith
|
gptkb:integrins
gptkb:ERp57
gptkb:SERCA2
gptkb:calnexin
|
|
gptkbp:involves
|
protein folding
immune response
apoptosis regulation
cell adhesion
antigen presentation
quality control of glycoproteins
|
|
gptkbp:locatedOnChromosome
|
gptkb:19p13.2
|
|
gptkbp:location
|
endoplasmic reticulum lumen
|
|
gptkbp:molecularWeight
|
46 kDa
|
|
gptkbp:mutationAssociatedWith
|
frameshift mutation
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Calr
|
|
gptkbp:orthologInYeast
|
Crt1
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:sequence
|
417 amino acids
|
|
gptkbp:structure
|
C-domain
N-domain
P-domain
|
|
gptkbp:UniProtID
|
P27797
|
|
gptkbp:bfsParent
|
gptkb:CALR
|
|
gptkbp:bfsLayer
|
7
|