|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:CRP55
gptkb:ERp60
gptkb:cC1qR
calregulin
|
|
gptkbp:associatedWith
|
essential thrombocythemia
primary myelofibrosis
myeloproliferative neoplasms
|
|
gptkbp:cellularComponent
|
gptkb:endoplasmic_reticulum
|
|
gptkbp:component
|
endoplasmic reticulum lumen
|
|
gptkbp:discoveredIn
|
1974
|
|
gptkbp:encodes
|
gptkb:calreticulin
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000179218
811
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
gptkb:calreticulin
|
|
gptkbp:function
|
protein folding
regulation of gene expression
protein binding
calcium ion binding
calcium-binding chaperone
|
|
gptkbp:GOProcess
|
protein folding
response to endoplasmic reticulum stress
|
|
gptkbp:HGNC_ID
|
1455
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CALR
|
|
gptkbp:interactsWith
|
gptkb:C1q
gptkb:ERp57
gptkb:SERCA2
gptkb:calnexin
|
|
gptkbp:length
|
417 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:19p13.2
|
|
gptkbp:molecularWeight
|
46 kDa
|
|
gptkbp:mutationAssociatedWith
|
frameshift mutation
|
|
gptkbp:OMIM
|
109091
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Calr
|
|
gptkbp:PDB
|
gptkb:6ENY
gptkb:6ENZ
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:regulates
|
apoptosis
immune response
integrin-mediated cell adhesion
|
|
gptkbp:subcellularLocation
|
gptkb:endoplasmic_reticulum
gptkb:nucleus
gptkb:cytoplasm
cell surface
|
|
gptkbp:UniProtID
|
P27797
|
|
gptkbp:bfsParent
|
gptkb:myelofibrosis
|
|
gptkbp:bfsLayer
|
6
|