|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:binds
|
calcium ions
|
|
gptkbp:discoveredBy
|
gptkb:Masatoshi_Takeichi
|
|
gptkbp:domain
|
extracellular cadherin repeats
|
|
gptkbp:example
|
gptkb:E-cadherin
gptkb:N-cadherin
gptkb:VE-cadherin
gptkb:P-cadherin
|
|
gptkbp:firstDescribed
|
1977
|
|
gptkbp:foundIn
|
animals
|
|
gptkbp:function
|
cell adhesion
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
cadherin
|
|
gptkbp:interactsWith
|
catenins
|
|
gptkbp:involvedIn
|
embryonic development
tissue morphogenesis
maintenance of tissue structure
|
|
gptkbp:locale
|
gptkb:plasma_membrane
|
|
gptkbp:medium
|
homophilic cell-cell adhesion
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
developmental disorders
|
|
gptkbp:proteinFamily
|
gptkb:CDH
|
|
gptkbp:requires
|
calcium for function
|
|
gptkbp:role
|
cell signaling
epithelial-mesenchymal transition
synapse formation
contact inhibition
|
|
gptkbp:subclassOf
|
classical cadherins
protocadherins
atypical cadherins
desmosomal cadherins
|
|
gptkbp:type
|
transmembrane protein
|
|
gptkbp:bfsParent
|
gptkb:DSC3
gptkb:DSG2
|
|
gptkbp:bfsLayer
|
7
|