blastic plasmacytoid dendritic cell neoplasm
GPTKB entity
Statements (39)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
leukemia
rare cancer |
| gptkbp:abbreviation |
BPDCN
|
| gptkbp:affects |
gptkb:plasmacytoid_dendritic_cells
|
| gptkbp:affectsGender |
male
|
| gptkbp:alternativeName |
CD4+/CD56+ hematodermic neoplasm
agranular CD4+ natural killer cell leukemia blastic NK-cell lymphoma |
| gptkbp:firstDescribed |
1994
|
| gptkbp:hasGeneticAlteration |
gptkb:TP53_mutation
ASXL1 mutation MYC rearrangement TET2 mutation |
| https://www.w3.org/2000/01/rdf-schema#label |
blastic plasmacytoid dendritic cell neoplasm
|
| gptkbp:ICD-10_code |
C86.6
|
| gptkbp:incidence |
<1% of hematologic malignancies
|
| gptkbp:marking |
gptkb:CD56
gptkb:CD4 gptkb:CD123 gptkb:BDCA-2 TCL1 BDCA-4 |
| gptkbp:medianAge |
60 years
|
| gptkbp:primarySite |
gptkb:skin
blood lymph nodes bone marrow |
| gptkbp:prognosis |
poor
|
| gptkbp:symptom |
fever
fatigue skin lesions cytopenias enlarged lymph nodes |
| gptkbp:treatment |
chemotherapy
stem cell transplantation tagraxofusp |
| gptkbp:WHOClassification |
myeloid neoplasm
|
| gptkbp:bfsParent |
gptkb:UCART123
|
| gptkbp:bfsLayer |
8
|