blastic plasmacytoid dendritic cell neoplasm

URI: https://gptkb.org/entity/blastic_plasmacytoid_dendritic_cell_neoplasm
GPTKB entity
Statements (39)
Predicate Object
gptkbp:instanceOf gptkb:leukemia
gptkb:rare_cancer
gptkbp:abbreviation BPDCN
gptkbp:affects gptkb:plasmacytoid_dendritic_cells
gptkbp:affectsGender gptkb:male
gptkbp:alternativeName CD4+/CD56+ hematodermic neoplasm
agranular CD4+ natural killer cell leukemia
blastic NK-cell lymphoma
gptkbp:firstDescribed 1994
gptkbp:hasGeneticAlteration gptkb:TP53_mutation
ASXL1 mutation
MYC rearrangement
TET2 mutation
gptkbp:ICD-10_code C86.6
gptkbp:incidence <1% of hematologic malignancies
gptkbp:marking gptkb:CD56
gptkb:CD4
gptkb:CD123
gptkb:BDCA-2
TCL1
BDCA-4
gptkbp:medianAge 60 years
gptkbp:primarySite gptkb:skin
blood
lymph nodes
bone marrow
gptkbp:prognosis poor
gptkbp:symptom fever
fatigue
skin lesions
cytopenias
enlarged lymph nodes
gptkbp:treatment chemotherapy
stem cell transplantation
tagraxofusp
gptkbp:WHOClassification myeloid neoplasm
gptkbp:bfsParent gptkb:UCART123
gptkbp:bfsLayer 8
https://www.w3.org/2000/01/rdf-schema#label blastic plasmacytoid dendritic cell neoplasm