Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
protein fragment
|
gptkbp:accumulatesIn |
extracellular space
|
gptkbp:alsoKnownAs |
gptkb:Aβ
|
gptkbp:associatedWith |
gptkb:Alzheimer's_disease
|
gptkbp:cleavage |
gptkb:beta-secretase
gptkb:gamma-secretase |
gptkbp:composedOf |
amino acids
|
gptkbp:derivedFrom |
gptkb:amyloid_precursor_protein
|
gptkbp:discoveredBy |
gptkb:George_Glenner
|
gptkbp:discoveredIn |
1984
|
gptkbp:existsIn |
monomers
fibrils oligomers |
gptkbp:form |
amyloid plaques
|
gptkbp:foundIn |
brain
|
https://www.w3.org/2000/01/rdf-schema#label |
beta-amyloid
|
gptkbp:involves |
neurodegeneration
|
gptkbp:sequence |
39-43 amino acids
|
gptkbp:studiedIn |
Alzheimer's research
|
gptkbp:target |
immunotherapy
|
gptkbp:toxicity |
neurons
|
gptkbp:bfsParent |
gptkb:GM1_ganglioside
|
gptkbp:bfsLayer |
7
|