GM1 ganglioside

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf ganglioside
glycosphingolipid
gptkbp:binds gptkb:cholera_toxin
gptkb:beta-amyloid
gptkbp:biosynthesized_from gptkb:lactosylceramide
gptkbp:CASNumber gptkb:37758-47-7
gptkbp:chemicalFormula C73H131N3O31
gptkbp:component lipid rafts
gptkbp:deficiencyCauses gptkb:GM1_gangliosidosis
gptkbp:degradedBy gptkb:beta-galactosidase
gptkbp:foundIn gptkb:cell_membrane
neuronal tissue
gptkbp:hasRole mediator of cell adhesion
modulator of synaptic plasticity
regulator of neuroinflammation
https://www.w3.org/2000/01/rdf-schema#label GM1 ganglioside
gptkbp:IUPACName (2S,3R,4E)-2-[(2R,3S,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxy-4-[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-(N-acetyl-2-amino-2-deoxy-beta-D-galactopyranosyl)-N-acetylneuraminic acid
gptkbp:PubChem_CID gptkb:CHEBI:28848
439324
gptkbp:role cell signaling
neuroprotection
modulation of ion channels
modulation of neurotransmitter receptors
modulation of neurotrophic factors
gptkbp:usedAs biomarker for neurodegenerative diseases
therapeutic agent in neurological disorders
gptkbp:bfsParent gptkb:cholera_toxin
gptkbp:bfsLayer 6