Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
ganglioside
glycosphingolipid |
gptkbp:binds |
gptkb:cholera_toxin
gptkb:beta-amyloid |
gptkbp:biosynthesized_from |
gptkb:lactosylceramide
|
gptkbp:CASNumber |
gptkb:37758-47-7
|
gptkbp:chemicalFormula |
C73H131N3O31
|
gptkbp:component |
lipid rafts
|
gptkbp:deficiencyCauses |
gptkb:GM1_gangliosidosis
|
gptkbp:degradedBy |
gptkb:beta-galactosidase
|
gptkbp:foundIn |
gptkb:cell_membrane
neuronal tissue |
gptkbp:hasRole |
mediator of cell adhesion
modulator of synaptic plasticity regulator of neuroinflammation |
https://www.w3.org/2000/01/rdf-schema#label |
GM1 ganglioside
|
gptkbp:IUPACName |
(2S,3R,4E)-2-[(2R,3S,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxy-4-[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-(N-acetyl-2-amino-2-deoxy-beta-D-galactopyranosyl)-N-acetylneuraminic acid
|
gptkbp:PubChem_CID |
gptkb:CHEBI:28848
439324 |
gptkbp:role |
cell signaling
neuroprotection modulation of ion channels modulation of neurotransmitter receptors modulation of neurotrophic factors |
gptkbp:usedAs |
biomarker for neurodegenerative diseases
therapeutic agent in neurological disorders |
gptkbp:bfsParent |
gptkb:cholera_toxin
|
gptkbp:bfsLayer |
6
|