Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:biologicalProcess |
amino acid metabolism
nitrogen metabolism arginase activity |
| gptkbp:catalyzes |
hydrolysis of arginine to ornithine and urea
|
| gptkbp:cofactor |
manganese
|
| gptkbp:discoveredBy |
gptkb:Kossel_and_Dakin
|
| gptkbp:EC_number |
3.5.3.1
|
| gptkbp:firstDescribed |
1904
|
| gptkbp:foundIn |
gptkb:kidney
liver red blood cells |
| gptkbp:gene |
gptkb:ARG2
ARG1 |
| gptkbp:hasIsoform |
gptkb:arginase_1
gptkb:arginase_2 |
| https://www.w3.org/2000/01/rdf-schema#label |
arginase
|
| gptkbp:inhibitedBy |
gptkb:NOHA_(N-hydroxy-L-arginine)
ornithine boronic acid derivatives |
| gptkbp:involves |
gptkb:urea_cycle
|
| gptkbp:presentIn |
gptkb:Bacteria
animals plants |
| gptkbp:product |
gptkb:urea
gptkb:L-ornithine |
| gptkbp:significance |
arginase deficiency causes argininemia
|
| gptkbp:structure |
homotrimer
|
| gptkbp:subcellularLocation |
mitochondria
cytosol |
| gptkbp:substrate |
gptkb:L-arginine
|
| gptkbp:used_in |
biochemical research
clinical diagnostics |
| gptkbp:bfsParent |
gptkb:urea_cycle
|
| gptkbp:bfsLayer |
5
|