Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
ARG1
liver-type arginase |
| gptkbp:catalyzes |
hydrolysis of arginine to ornithine and urea
|
| gptkbp:cofactor |
manganese
|
| gptkbp:deficiencyCauses |
argininemia
|
| gptkbp:EC_number |
3.5.3.1
|
| gptkbp:encodedBy |
ARG1 gene
|
| gptkbp:expressedIn |
gptkb:hepatocytes
|
| gptkbp:foundIn |
liver
erythrocytes |
| gptkbp:HGNC_ID |
HGNC:663
|
| https://www.w3.org/2000/01/rdf-schema#label |
arginase 1
|
| gptkbp:inhibitedBy |
boronic acid derivatives
Nω-hydroxy-nor-arginine (nor-NOHA) |
| gptkbp:involvedIn |
gptkb:urea_cycle
|
| gptkbp:locatedOnChromosome |
gptkb:6q23
|
| gptkbp:molecularWeight |
approximately 35 kDa
|
| gptkbp:OMIM |
608313
|
| gptkbp:orthologIn |
gptkb:mouse
right |
| gptkbp:PDB |
2AEB
|
| gptkbp:structure |
homotrimer
|
| gptkbp:UniProtID |
P05089
|
| gptkbp:usedIn |
diagnosis of liver function
|
| gptkbp:bfsParent |
gptkb:arginase
|
| gptkbp:bfsLayer |
6
|