Statements (97)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:binds |
major groove of DNA
|
| gptkbp:contains |
zinc finger domains
|
| gptkbp:discoveredBy |
gptkb:Aaron_Klug
|
| gptkbp:example |
gptkb:EGR1
gptkb:ZEB2 gptkb:SP1 gptkb:KLF4 gptkb:Krüppel-like_factors gptkb:ZEB1 gptkb:WT1 gptkb:Zif268 TFIIIA ZFP36 PRDM9 GATA factors GLI proteins ZFP1000 ZFP106 ZFP1120 ZFP1130 ZFP1140 ZFP1150 ZFP1160 ZFP1170 ZFP1180 ZFP1190 ZFP1200 ZFP1210 ZFP1220 ZFP1230 ZFP1240 ZFP1250 ZFP1260 ZFP1270 ZFP1280 ZFP1290 ZFP1300 ZFP1310 ZFP1320 ZFP1330 ZFP1340 ZFP1350 ZFP1360 ZFP1370 ZFP1380 ZFP1390 ZFP1400 ZFP1410 ZFP1420 ZFP1430 ZFP1440 ZFP1450 ZFP1460 ZFP1470 ZFP1480 ZFP1490 ZFP1500 ZFP423 ZFP521 ZFP57 ZFP809 ZFP819 ZFP91 ZFP942 ZFP961 ZFP982 ZFP985 ZNF family |
| gptkbp:firstDescribed |
1980s
|
| gptkbp:foundIn |
prokaryotes
eukaryotes |
| gptkbp:function |
protein-protein interaction
RNA binding DNA binding |
| https://www.w3.org/2000/01/rdf-schema#label |
Zinc finger proteins
|
| gptkbp:motif |
Treble clef
Cys2His2 Cys4 Cys6 Gag knuckle Zinc ribbon |
| gptkbp:number_of_types |
over 30
|
| gptkbp:role |
apoptosis
cell differentiation development DNA repair transcriptional activation gene regulation transcriptional repression chromatin remodeling |
| gptkbp:used_in |
gptkb:biotechnology
synthetic biology genome editing zinc finger nucleases |
| gptkbp:bfsParent |
gptkb:TALE_proteins
|
| gptkbp:bfsLayer |
7
|