ZNF217

GPTKB entity

Statements (46)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alias ZNF217 zinc finger protein
Zinc finger protein 217
gptkbp:associatedWith gptkb:cancer
gptkbp:biologicalProcess DNA binding
transcription factor activity
gptkbp:discoveredBy Collins et al.
gptkbp:encodes Zinc finger protein 217
gptkbp:Entrez_Gene_ID 7764
ENSG00000148516
gptkbp:expressedIn gptkb:nucleus
various tissues
gptkbp:firstDescribed 1998
gptkbp:function tumor suppressor
transcriptional regulation
gptkbp:GOID GO:0003700
GO:0006355
gptkbp:HGNC_ID HGNC:13022
https://www.w3.org/2000/01/rdf-schema#label ZNF217
gptkbp:interactsWith gptkb:KDM5B
gptkb:LSD1
gptkb:CoREST
CtBP1
HDACs
gptkbp:involves gptkb:cancer
colorectal cancer
pancreatic cancer
prostate cancer
gptkbp:length 1046 amino acids
242,000 bp
gptkbp:locatedOnChromosome gptkb:20q13.2
gptkbp:mutationAssociatedWith amplification
overexpression
gptkbp:numberOfExons 10
gptkbp:OMIM 603472
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse Zfp217
gptkbp:overexpressedIn tumors
gptkbp:proteinFamily zinc finger protein
gptkbp:regulates apoptosis
cell proliferation
cell cycle
gptkbp:species gptkb:human
gptkbp:UniProtID O75362
gptkbp:bfsParent gptkb:20q13.2
gptkbp:bfsLayer 7