Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:associatedWith |
neurodegenerative diseases
cancer susceptibility |
| gptkbp:discoveredIn |
1990s
|
| gptkbp:encodes |
XRCC1 protein
|
| gptkbp:Entrez_Gene_ID |
ENSG00000169047
7515 |
| gptkbp:expressedIn |
gptkb:nucleus
|
| gptkbp:fullName |
X-ray repair cross-complementing protein 1
|
| gptkbp:function |
scaffold protein in DNA repair
|
| gptkbp:hasPolymorphism |
Arg194Trp
Arg280His Arg399Gln |
| gptkbp:HGNC_ID |
12828
|
| https://www.w3.org/2000/01/rdf-schema#label |
XRCC1
|
| gptkbp:interactsWith |
gptkb:PARP1
gptkb:DNA_ligase_III POLB |
| gptkbp:involvedIn |
DNA repair
base excision repair |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_19
19q13.2 |
| gptkbp:OMIM |
194360
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:RefSeq |
NM_006297
|
| gptkbp:UniProtID |
P18887
|
| gptkbp:bfsParent |
gptkb:PARP1
gptkb:PARP3 |
| gptkbp:bfsLayer |
7
|