|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:Wnt-5a
gptkb:wingless-type_MMTV_integration_site_family,_member_5A
|
|
gptkbp:biologicalProcess
|
signaling molecule
|
|
gptkbp:discoveredBy
|
gptkb:Nusse_and_Varmus
|
|
gptkbp:discoveredIn
|
1982
|
|
gptkbp:encodedBy
|
Wnt5a gene (mouse)
|
|
gptkbp:Entrez_Gene_ID
|
22418
ENSMUSG00000021963
|
|
gptkbp:expressedIn
|
embryonic tissues
mesenchyme
developing limb bud
|
|
gptkbp:function
|
embryonic development
cell signaling
regulation of cell fate
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Wnt5a (mouse)
|
|
gptkbp:involvedIn
|
cell migration
organogenesis
non-canonical Wnt signaling pathway
planar cell polarity pathway
limb development
|
|
gptkbp:locatedOnChromosome
|
gptkb:mouse_chromosome_6
|
|
gptkbp:memberOf
|
gptkb:Wnt_family
|
|
gptkbp:mutationAssociatedWith
|
limb malformation
defective organ development
|
|
gptkbp:organism
|
gptkb:Mus_musculus
|
|
gptkbp:orthologIn
|
WNT5A (human)
|
|
gptkbp:pathway
|
gptkb:Wnt_signaling_pathway
calcium signaling pathway
planar cell polarity pathway
|
|
gptkbp:postTranslationalModification
|
palmitoylation
glycosylation
|
|
gptkbp:recipient
|
gptkb:Frizzled_receptors
gptkb:ROR2
gptkb:RYK
|
|
gptkbp:regulates
|
apoptosis
cell proliferation
cell migration
cell polarity
tissue morphogenesis
|
|
gptkbp:relatedDiseaseModel
|
Robinow syndrome (mouse model)
limb deformities (mouse model)
|
|
gptkbp:type
|
secreted glycoprotein
|
|
gptkbp:UniProtID
|
P22725
|
|
gptkbp:bfsParent
|
gptkb:Wnt-5a
gptkb:Wnt5a
|
|
gptkbp:bfsLayer
|
8
|