Werner syndrome ATP-dependent helicase
GPTKB entity
Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:WRN_protein
|
| gptkbp:associatedWith |
genomic instability
premature aging |
| gptkbp:discoveredBy |
Shunichi Araki et al.
|
| gptkbp:encodedBy |
gptkb:WRN_gene
|
| gptkbp:function |
ATPase activity
DNA helicase activity exonuclease activity |
| gptkbp:GO |
GO:0006281
GO:0004386 |
| https://www.w3.org/2000/01/rdf-schema#label |
Werner syndrome ATP-dependent helicase
|
| gptkbp:involvedIn |
DNA repair
genomic stability |
| gptkbp:locatedOnChromosome |
gptkb:8p12
|
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:molecularWeight |
162 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:Werner_syndrome
|
| gptkbp:OMIM |
604611
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:structure |
contains helicase and exonuclease domains
|
| gptkbp:UniProtID |
gptkb:Q14191
|
| gptkbp:bfsParent |
gptkb:WRN_(human)
|
| gptkbp:bfsLayer |
7
|