|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
wingless-type MMTV integration site family, member 4
WNT-4
Wnt4a
|
|
gptkbp:associatedWith
|
disorders of sex development
premature ovarian failure
Mayer-Rokitansky-Küster-Hauser syndrome
|
|
gptkbp:discoveredBy
|
Nusse and Varmus lab
|
|
gptkbp:encodes
|
gptkb:Wnt-4_protein
|
|
gptkbp:Entrez_Gene_ID
|
54361
ENSG00000162552
|
|
gptkbp:expressedIn
|
gptkb:adrenal_gland
gptkb:kidney
gptkb:testis
|
|
gptkbp:firstDescribed
|
1992
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
12786
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
WNT4 gene
|
|
gptkbp:involvedIn
|
embryonic development
cell signaling
sex determination
kidney development
female reproductive tract development
|
|
gptkbp:locatedOnChromosome
|
chromosome 1
1p36.12
|
|
gptkbp:memberOf
|
gptkb:WNT_gene_family
|
|
gptkbp:mutationAssociatedWith
|
gptkb:46,XX_sex_reversal
gptkb:SERKAL_syndrome
Müllerian duct regression
|
|
gptkbp:OMIM
|
603490
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Wnt4
|
|
gptkbp:pathway
|
gptkb:Wnt_signaling_pathway
|
|
gptkbp:product
|
Wnt-4
|
|
gptkbp:proteinFamily
|
gptkb:Wnt_proteins
|
|
gptkbp:regulates
|
gonadal differentiation
mesonephric development
folliculogenesis
uterine development
|
|
gptkbp:UniProtID
|
P56705
|
|
gptkbp:bfsParent
|
gptkb:SERKAL_syndrome
gptkb:Wnt-4_protein
|
|
gptkbp:bfsLayer
|
8
|