|
gptkbp:instanceOf
|
gptkb:nuclear_receptor
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:VDR
|
|
gptkbp:associatedWith
|
hereditary vitamin D-resistant rickets
|
|
gptkbp:binds
|
gptkb:calcitriol
gptkb:1,25-dihydroxyvitamin_D3
|
|
gptkbp:biologicalProcess
|
DNA binding
transcription factor activity
|
|
gptkbp:discoveredBy
|
1980s
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000111424
|
|
gptkbp:expressedIn
|
gptkb:bone
gptkb:kidney
parathyroid gland
intestine
immune cells
|
|
gptkbp:formsComplexWith
|
gptkb:retinoid_X_receptor_(RXR)
|
|
gptkbp:foundIn
|
humans
mammals
|
|
gptkbp:function
|
regulates gene expression
mediates effects of vitamin D
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:12679
|
|
gptkbp:locatedOnChromosome
|
chromosome 12q13.11 (human)
|
|
gptkbp:location
|
cell nucleus
|
|
gptkbp:OMIM
|
601769
|
|
gptkbp:PDB
|
gptkb:1DB1
|
|
gptkbp:product
|
VDR gene
|
|
gptkbp:regulates
|
calcium homeostasis
phosphate metabolism
vitamin D-responsive genes
|
|
gptkbp:UniProtID
|
P11473
|
|
gptkbp:bfsParent
|
gptkb:VDR
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Vitamin D3 receptor
|