Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
nuclear receptor |
| gptkbp:alternativeName |
gptkb:VDR
|
| gptkbp:associatedWith |
hereditary vitamin D-resistant rickets
|
| gptkbp:binds |
gptkb:calcitriol
gptkb:1,25-dihydroxyvitamin_D3 |
| gptkbp:biologicalProcess |
DNA binding
transcription factor activity |
| gptkbp:discoveredBy |
1980s
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000111424
|
| gptkbp:expressedIn |
gptkb:bone
gptkb:kidney parathyroid gland intestine immune cells |
| gptkbp:formsComplexWith |
gptkb:retinoid_X_receptor_(RXR)
|
| gptkbp:foundIn |
humans
mammals |
| gptkbp:function |
regulates gene expression
mediates effects of vitamin D |
| gptkbp:HGNC_ID |
gptkb:HGNC:12679
|
| https://www.w3.org/2000/01/rdf-schema#label |
Vitamin D3 receptor
|
| gptkbp:locatedOnChromosome |
chromosome 12q13.11 (human)
|
| gptkbp:location |
cell nucleus
|
| gptkbp:OMIM |
601769
|
| gptkbp:PDB |
gptkb:1DB1
|
| gptkbp:product |
VDR gene
|
| gptkbp:regulates |
calcium homeostasis
phosphate metabolism vitamin D-responsive genes |
| gptkbp:UniProtID |
P11473
|
| gptkbp:bfsParent |
gptkb:VDR
|
| gptkbp:bfsLayer |
7
|