Statements (42)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
vitamin D metabolite
secosteroid hormone |
| gptkbp:approvedDrugIn |
gptkb:United_States
|
| gptkbp:ATCCode |
A11CC04
|
| gptkbp:biosynthesized_from |
gptkb:vitamin_A
gptkb:kidney |
| gptkbp:CASNumber |
32222-06-3
|
| gptkbp:category |
hormone
vitamin D metabolite secosteroid |
| gptkbp:chemicalFormula |
C27H44O3
|
| gptkbp:deactivatedIn |
gptkb:kidney
liver |
| gptkbp:deactivationEnzyme |
24-hydroxylase
|
| gptkbp:discoveredBy |
Anthony W. Norman
Hector DeLuca |
| gptkbp:firstDescribed |
1971
|
| gptkbp:function |
regulation of phosphate homeostasis
modulation of immune system regulation of calcium homeostasis bone mineralization promotion of intestinal calcium absorption |
| https://www.w3.org/2000/01/rdf-schema#label |
1,25-dihydroxyvitamin D3
|
| gptkbp:IUPACName |
(1R,3S,5Z,7E,22E)-9,10-secocholesta-5,7,10(19),22-tetraene-1,3,25-triol
|
| gptkbp:meltingPoint |
120-125°C
|
| gptkbp:molecularWeight |
416.64 g/mol
|
| gptkbp:otherName |
gptkb:calcitriol
|
| gptkbp:predecessor |
gptkb:25-hydroxyvitamin_D3
|
| gptkbp:PubChem_CID |
5280453
CHEMBL1204 |
| gptkbp:recipient |
vitamin D receptor
|
| gptkbp:routeOfAdministration |
oral
intravenous |
| gptkbp:solubility |
insoluble in water
soluble in ethanol soluble in chloroform |
| gptkbp:UNII |
FXC9231JVH
|
| gptkbp:usedFor |
gptkb:secondary_hyperparathyroidism
hypocalcemia renal osteodystrophy |
| gptkbp:bfsParent |
gptkb:25-hydroxyvitamin_D3
|
| gptkbp:bfsLayer |
6
|