|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:PIK3C3
|
|
gptkbp:associatedWith
|
gptkb:cancer
neurodegenerative diseases
|
|
gptkbp:biologicalProcess
|
kinase activity
autophagosome formation
membrane trafficking
|
|
gptkbp:encodedBy
|
gptkb:PIK3C3_gene
|
|
gptkbp:Entrez_Gene_ID
|
5289
|
|
gptkbp:enzymeClassification
|
gptkb:EC_2.7.1.137
|
|
gptkbp:formsComplexWith
|
gptkb:Beclin-1
gptkb:ATG14L
gptkb:UVRAG
|
|
gptkbp:fullName
|
Vacuolar protein sorting 34 homolog
|
|
gptkbp:function
|
phosphatidylinositol 3-kinase activity
|
|
gptkbp:HGNC_ID
|
8975
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
VPS34
|
|
gptkbp:involvedIn
|
autophagy
endocytosis
vesicle-mediated transport
|
|
gptkbp:locatedOnChromosome
|
18q12.3
|
|
gptkbp:location
|
gptkb:cytoplasm
endosomes
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae
|
|
gptkbp:PDB
|
6DPU
|
|
gptkbp:regulates
|
gptkb:mTOR_signaling_pathway
|
|
gptkbp:target
|
small molecule inhibitors
|
|
gptkbp:UniProtID
|
gptkb:Q8NEB9
|
|
gptkbp:bfsParent
|
gptkb:PIK3C3
gptkb:PIK3C3_gene
|
|
gptkbp:bfsLayer
|
6
|