VIM-type metallo-beta-lactamases
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:cofactor |
zinc
|
| gptkbp:detects |
PCR
phenotypic tests |
| gptkbp:enzymeClassification |
metallo-beta-lactamase
|
| gptkbp:firstDescribed |
1999
|
| gptkbp:foundIn |
gptkb:Enterobacteriaceae
gptkb:Pseudomonas_aeruginosa gptkb:Klebsiella_pneumoniae |
| gptkbp:function |
hydrolyze beta-lactam antibiotics
|
| gptkbp:gene |
blaVIM
|
| https://www.w3.org/2000/01/rdf-schema#label |
VIM-type metallo-beta-lactamases
|
| gptkbp:inhibitedBy |
gptkb:clavulanic_acid
gptkb:sulbactam gptkb:EDTA tazobactam |
| gptkbp:publicHealthConcern |
antibiotic resistance
|
| gptkbp:resistantTo |
gptkb:cephalosporins
penicillins carbapenems |
| gptkbp:spreadTo |
horizontal gene transfer
|
| gptkbp:subclassOf |
class B beta-lactamase
|
| gptkbp:variantExamples |
gptkb:VIM-1
gptkb:VIM-2 gptkb:VIM-4 gptkb:VIM-5 gptkb:VIM-7 |
| gptkbp:bfsParent |
gptkb:IMP-I
|
| gptkbp:bfsLayer |
7
|