|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:VAV
VAV proto-oncogene 1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:T_cell_receptor_signaling_pathway
immune response
|
|
gptkbp:discoveredBy
|
gptkb:Dr._Mariano_Barbacid
|
|
gptkbp:encodes
|
Vav1 protein
|
|
gptkbp:Entrez_Gene_ID
|
7409
ENSG00000120963
|
|
gptkbp:expressedIn
|
hematopoietic cells
|
|
gptkbp:firstDescribed
|
1992
|
|
gptkbp:function
|
signal transduction
guanine nucleotide exchange factor activity
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:12657
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
VAV1 gene
|
|
gptkbp:length
|
~13 kb
|
|
gptkbp:locatedOnChromosome
|
gptkb:19p13.2
gptkb:chromosome_19
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
immunodeficiency
|
|
gptkbp:numberOfExons
|
27
|
|
gptkbp:OMIM
|
193163
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Vav1
|
|
gptkbp:proteinFamily
|
gptkb:PH_domain
gptkb:C1_domain
gptkb:Vav_family
SH2 domain
SH3 domain
DH domain
calponin homology domain
|
|
gptkbp:UniProtID
|
P15498
|
|
gptkbp:bfsParent
|
gptkb:Vav1
|
|
gptkbp:bfsLayer
|
7
|