|
gptkbp:instanceOf
|
biological pathway
|
|
gptkbp:alsoKnownAs
|
gptkb:ornithine_cycle
|
|
gptkbp:associatedWith
|
argininemia
argininosuccinic aciduria
carbamoyl phosphate synthetase I deficiency
citrullinemia
ornithine transcarbamylase deficiency
|
|
gptkbp:compatibleWith
|
amphibians
most fish
|
|
gptkbp:deficiencyCauses
|
hyperammonemia
|
|
gptkbp:discoveredBy
|
gptkb:Hans_Krebs
gptkb:Kurt_Henseleit
|
|
gptkbp:discoveredIn
|
1932
|
|
gptkbp:energyEfficiency
|
3 ATP per cycle
|
|
gptkbp:enzyme
|
gptkb:arginase
gptkb:argininosuccinate_lyase
gptkb:argininosuccinate_synthetase
gptkb:carbamoyl_phosphate_synthetase_I
gptkb:ornithine_transcarbamylase
|
|
gptkbp:fifthStep
|
formation of urea and ornithine
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Urea cycle
|
|
gptkbp:importantFor
|
detoxification of ammonia
|
|
gptkbp:location
|
liver
|
|
gptkbp:mainFunction
|
conversion of ammonia to urea
|
|
gptkbp:namedAfter
|
gptkb:urea
ornithine
|
|
gptkbp:numberOfStages
|
formation of carbamoyl phosphate
|
|
gptkbp:occurredIn
|
mitochondria
cytosol
|
|
gptkbp:presentIn
|
mammals
some terrestrial vertebrates
|
|
gptkbp:product
|
gptkb:water
gptkb:urea
fumarate
|
|
gptkbp:regulates
|
N-acetylglutamate
|
|
gptkbp:step
|
formation of arginine
formation of argininosuccinate
formation of citrulline
|
|
gptkbp:substrate
|
gptkb:aspartate
carbon dioxide
ammonia
|
|
gptkbp:bfsParent
|
gptkb:Glutamate
|
|
gptkbp:bfsLayer
|
6
|