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gptkbp:instanceOf
|
biological pathway
|
|
gptkbp:alsoKnownAs
|
gptkb:urea_cycle
|
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gptkbp:associatedWith
|
argininemia
argininosuccinic aciduria
carbamoyl phosphate synthetase I deficiency
citrullinemia
ornithine transcarbamylase deficiency
|
|
gptkbp:deficiencyCauses
|
hyperammonemia
|
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gptkbp:discoveredBy
|
gptkb:Hans_Krebs
gptkb:Kurt_Henseleit
|
|
gptkbp:enzyme
|
gptkb:arginase
gptkb:argininosuccinate_lyase
gptkb:argininosuccinate_synthetase
gptkb:carbamoyl_phosphate_synthetase_I
gptkb:ornithine_transcarbamylase
|
|
gptkbp:firstDescribed
|
1932
|
|
gptkbp:function
|
converts ammonia to urea
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ornithine cycle
|
|
gptkbp:importantFor
|
detoxifies ammonia
|
|
gptkbp:location
|
vertebrates
|
|
gptkbp:medium
|
arginine
argininosuccinate
citrulline
ornithine
|
|
gptkbp:namedAfter
|
ornithine
|
|
gptkbp:occurredIn
|
liver
mitochondria
cytosol
|
|
gptkbp:product
|
gptkb:urea
fumarate
|
|
gptkbp:regulates
|
N-acetylglutamate
|
|
gptkbp:substrate
|
carbon dioxide
ammonia
|
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gptkbp:bfsParent
|
gptkb:urea_cycle
|
|
gptkbp:bfsLayer
|
5
|