Topoisomerase IIβ-binding protein 1
GPTKB entity
Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:TOPBP1
DNA topoisomerase II beta-binding protein 1 |
| gptkbp:domain |
gptkb:BRCT_domain
|
| gptkbp:Entrez_Gene_ID |
ENSG00000107485
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
DNA replication
DNA damage response cell cycle checkpoint control |
| gptkbp:gene |
gptkb:TOPBP1
|
| https://www.w3.org/2000/01/rdf-schema#label |
Topoisomerase IIβ-binding protein 1
|
| gptkbp:interactsWith |
gptkb:ATR
gptkb:MDC1 gptkb:BRCA1 |
| gptkbp:involves |
DNA replication initiation
DNA damage checkpoint |
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
3q22.1
|
| gptkbp:molecularWeight |
180 kDa
|
| gptkbp:OMIM |
604990
|
| gptkbp:phosphorylates |
Ser1138
Ser1159 |
| gptkbp:RefSeq |
NM_007027
|
| gptkbp:UniProtID |
Q92547
|
| gptkbp:bfsParent |
gptkb:TopBP1
|
| gptkbp:bfsLayer |
7
|