Tissue inhibitor of metalloproteinases 3
GPTKB entity
Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:TIMP3
|
| gptkbp:associatedWith |
gptkb:Sorsby_fundus_dystrophy
|
| gptkbp:discoveredBy |
1992
|
| gptkbp:encodedBy |
gptkb:TIMP3_gene
|
| gptkbp:Entrez_Gene_ID |
7078
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
inhibits matrix metalloproteinases
regulates extracellular matrix |
| https://www.w3.org/2000/01/rdf-schema#label |
Tissue inhibitor of metalloproteinases 3
|
| gptkbp:inhibitedBy |
gptkb:MMP14
gptkb:MMP2 gptkb:MMP9 |
| gptkbp:locatedOnChromosome |
chromosome 22q12.1
|
| gptkbp:location |
extracellular space
|
| gptkbp:molecularWeight |
24 kDa
|
| gptkbp:OMIM |
188826
|
| gptkbp:postTranslationalModification |
glycosylation
|
| gptkbp:relatedTo |
apoptosis
angiogenesis inflammation |
| gptkbp:structure |
contains N-terminal and C-terminal domains
|
| gptkbp:UniProtID |
gptkb:P35625
|
| gptkbp:bfsParent |
gptkb:TIMP3
|
| gptkbp:bfsLayer |
7
|