Thyroid Cancer

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:cancer
gptkb:disease
gptkbp:affectsOrgan gptkb:Thyroid_gland
gptkbp:age Most common in adults aged 30-60
gptkbp:associatedWith gptkb:RAS_mutation
BRAF mutation
RET proto-oncogene mutation
gptkbp:diagnosedBy gptkb:CT_scan
MRI
Ultrasound
Blood tests
Fine needle aspiration biopsy
gptkbp:firstDescribed Described in medical literature since the 19th century
gptkbp:hasEpidemiology Most common endocrine malignancy
gptkbp:hasMetastasisSite gptkb:Bones
Lungs
Lymph nodes
gptkbp:hasScreening Not routinely recommended for general population
gptkbp:hasSurvivalRate 5-year survival rate over 98% for papillary type
Poor prognosis for anaplastic type
https://www.w3.org/2000/01/rdf-schema#label Thyroid Cancer
gptkbp:ICD-10_code gptkb:C73
gptkbp:incidence Incidence increasing worldwide
More common in women
gptkbp:mortalityRate Low for most types
gptkbp:prevalence Rare compared to other cancers
gptkbp:prevention Avoid unnecessary radiation exposure
Genetic counseling for high-risk families
gptkbp:prognosis Generally good for most types
gptkbp:riskFactor Family history
Genetic syndromes
Radiation exposure
gptkbp:stageName gptkb:TNM_staging
gptkbp:subspecies gptkb:Anaplastic_thyroid_cancer
gptkb:Follicular_thyroid_cancer
gptkb:Medullary_thyroid_cancer
gptkb:Papillary_thyroid_cancer
gptkbp:symptom Difficulty swallowing
Hoarseness
Neck lump
Swollen lymph nodes
gptkbp:treatment Surgery
Chemotherapy
Targeted therapy
External beam radiation therapy
Radioactive iodine therapy
Thyroid hormone therapy
gptkbp:bfsParent gptkb:D014842
gptkbp:bfsLayer 6