Papillary thyroid cancer

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:cancer
gptkbp:5YearSurvivalRate over 95%
gptkbp:associatedWith gptkb:RAS_mutation
gptkb:RET/PTC_rearrangement
BRAF mutation
gptkbp:canMetastasizeTo lungs
lymph nodes
bones
gptkbp:commonAgeGroup 30-50 years
gptkbp:commonIn females
gptkbp:commonInChildren rare
gptkbp:diagnosedBy ultrasound
histopathology
fine needle aspiration biopsy
gptkbp:differentialDiagnosis gptkb:anaplastic_thyroid_cancer
follicular thyroid cancer
medullary thyroid cancer
benign thyroid nodule
gptkbp:firstDescribed 1880s
gptkbp:followedBy neck ultrasound
serum thyroglobulin measurement
gptkbp:histology Orphan Annie eye nuclei
nuclear grooves
psammoma bodies
https://www.w3.org/2000/01/rdf-schema#label Papillary thyroid cancer
gptkbp:ICD-10_code gptkb:C73
gptkbp:mostCommonThyroidCancer true
gptkbp:originatedIn thyroid follicular cells
gptkbp:percentageOfThyroidCancers about 80%
gptkbp:prognosis generally excellent
gptkbp:recurrence about 10-20%
gptkbp:recurrenceSite cervical lymph nodes
distant organs
thyroid bed
gptkbp:riskFactor family history
radiation exposure
genetic syndromes
gptkbp:stagingSystem gptkb:AJCC_TNM
gptkbp:subspecies gptkb:diffuse_sclerosing_variant_papillary_thyroid_cancer
gptkb:follicular_variant_papillary_thyroid_cancer
gptkb:tall_cell_variant_papillary_thyroid_cancer
gptkbp:symptom lymphadenopathy
neck mass
thyroid nodule
gptkbp:treatment radioactive iodine therapy
thyroidectomy
thyroid hormone suppression therapy
gptkbp:bfsParent gptkb:cancer
gptkbp:bfsLayer 4