|
gptkbp:instanceOf
|
gptkb:cancer
Neuroendocrine Tumor
|
|
gptkbp:affects
|
thyroid gland
|
|
gptkbp:associatedWith
|
gptkb:Familial_medullary_thyroid_carcinoma
gptkb:RET_proto-oncogene
gptkb:Multiple_Endocrine_Neoplasia_type_2A
gptkb:Multiple_Endocrine_Neoplasia_type_2B
|
|
gptkbp:canBeSporadic
|
true
|
|
gptkbp:canMetastasizeTo
|
gptkb:bone
lungs
liver
lymph nodes
|
|
gptkbp:diagnosedBy
|
RET genetic testing
calcitonin blood test
fine needle aspiration
|
|
gptkbp:doesNotRespondTo
|
radioactive iodine
|
|
gptkbp:firstDescribed
|
gptkb:Jacques_Forestier
1959
|
|
gptkbp:hereditary
|
true
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Medullary thyroid cancer
|
|
gptkbp:ICD-10_code
|
gptkb:C73
|
|
gptkbp:incidence
|
about 3-5% of thyroid cancers
|
|
gptkbp:marking
|
gptkb:calcitonin
gptkb:carcinoembryonic_antigen
|
|
gptkbp:MeSH_ID
|
D013964
|
|
gptkbp:OMIM
|
155240
|
|
gptkbp:originatedIn
|
parafollicular C cells
|
|
gptkbp:prognosis
|
stage at diagnosis
presence of metastasis
|
|
gptkbp:symptom
|
diarrhea
hoarseness
dysphagia
neck mass
|
|
gptkbp:treatment
|
radiation therapy
targeted therapy
thyroidectomy
lymph node dissection
|
|
gptkbp:UMLS_CUI
|
C0027750
|
|
gptkbp:bfsParent
|
gptkb:cancer
|
|
gptkbp:bfsLayer
|
4
|