|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:BCMA
gptkb:CD269
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:systemic_lupus_erythematosus
multiple myeloma
|
|
gptkbp:biologicalProcess
|
immune response
B cell activation
cytokine receptor activity
|
|
gptkbp:cellSurfaceMarker
|
gptkb:B_cells
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredBy
|
E. Thompson et al.
|
|
gptkbp:encodes
|
gptkb:B-cell_maturation_antigen
|
|
gptkbp:Entrez_Gene_ID
|
608
ENSG00000048462
|
|
gptkbp:expressedIn
|
gptkb:B_lymphocytes
|
|
gptkbp:fullName
|
gptkb:Tumor_necrosis_factor_receptor_superfamily_member_17
|
|
gptkbp:function
|
receptor for BAFF and APRIL
regulates B cell development and survival
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
11910
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TNFRSF17
|
|
gptkbp:length
|
184 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:16p13.13
|
|
gptkbp:memberOf
|
gptkb:tumor_necrosis_factor_receptor_superfamily
|
|
gptkbp:OMIM
|
gptkb:603972
|
|
gptkbp:orthologInMouse
|
gptkb:Tnfrsf17
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:targetOfDrug
|
gptkb:idecabtagene_vicleucel
gptkb:belantamab_mafodotin
gptkb:ciltacabtagene_autoleucel
|
|
gptkbp:transmembraneDomains
|
true
|
|
gptkbp:UniProtID
|
gptkb:Q02223
|
|
gptkbp:bfsParent
|
gptkb:BCMA
|
|
gptkbp:bfsLayer
|
6
|