|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
autoimmune diseases
encephalitis
viral infection response
|
|
gptkbp:component
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredBy
|
gptkb:Bruce_Beutler
|
|
gptkbp:encodes
|
Toll-like receptor 3 protein
|
|
gptkbp:Entrez_Gene_ID
|
7098
ENSG00000164342
|
|
gptkbp:expressedIn
|
immune cells
epithelial cells
|
|
gptkbp:fullName
|
gptkb:Toll-like_receptor_3
|
|
gptkbp:function
|
innate immune response
double-stranded RNA binding
recognition of double-stranded RNA
|
|
gptkbp:GOProcess
|
innate immune response
|
|
gptkbp:HGNC_ID
|
HGNC:11849
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TLR3 gene
|
|
gptkbp:length
|
904 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_4
4q35
|
|
gptkbp:molecularWeight
|
104 kDa
|
|
gptkbp:mutationAssociatedWith
|
increased susceptibility to viral infection
|
|
gptkbp:OMIM
|
603029
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Tlr3
|
|
gptkbp:PDB
|
2A0Z
|
|
gptkbp:proteinFamily
|
gptkb:Toll-like_receptor_family
|
|
gptkbp:reactomeID
|
R-HSA-168164
|
|
gptkbp:symbol
|
gptkb:TLR3
|
|
gptkbp:UniProtID
|
O15455
|
|
gptkbp:bfsParent
|
gptkb:CD283
gptkb:TLR3
|
|
gptkbp:bfsLayer
|
8
|