|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:TIMP4
TIMP-4
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:cardiovascular_disease
|
|
gptkbp:biologicalProcess
|
extracellular matrix organization
negative regulation of cell migration
metalloendopeptidase inhibitor activity
negative regulation of angiogenesis
|
|
gptkbp:discoveredBy
|
1996
|
|
gptkbp:encodes
|
TIMP4 protein
|
|
gptkbp:Entrez_Gene_ID
|
7079
ENSG00000137801
GC03P022282
|
|
gptkbp:expressedIn
|
gptkb:placenta
brain
heart
pancreas
|
|
gptkbp:fullName
|
Tissue Inhibitor of Metalloproteinases 4
|
|
gptkbp:function
|
inhibits matrix metalloproteinases
regulates extracellular matrix composition
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:11821
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TIMP4 gene
|
|
gptkbp:length
|
5 exons
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_3
3p25.2
|
|
gptkbp:OMIM
|
601915
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Timp4
|
|
gptkbp:pathway
|
gptkb:ECM-receptor_interaction
gptkb:Focal_adhesion
|
|
gptkbp:proteinFamily
|
gptkb:TIMP_family
|
|
gptkbp:UniProtID
|
Q99727
|
|
gptkbp:bfsParent
|
gptkb:TIMP4
|
|
gptkbp:bfsLayer
|
7
|