Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alias |
gptkb:KLF10
EGRalpha TGF-beta-inducible early gene 1 protein |
| gptkbp:discoveredBy |
Subramaniam et al.
|
| gptkbp:discoveredIn |
1995
|
| gptkbp:encodedBy |
KLF10 gene
|
| gptkbp:Entrez_Gene_ID |
7071
|
| gptkbp:expressedIn |
gptkb:cancer
gptkb:bone gptkb:skeletal_muscle gptkb:prostate gptkb:testis heart liver pancreas |
| gptkbp:family |
gptkb:Kruppel-like_factor_family
|
| gptkbp:fullName |
Transforming growth factor-beta-inducible early growth response protein 1
|
| gptkbp:function |
transcription factor
regulates apoptosis regulates cell growth mediates TGF-beta signaling |
| gptkbp:gene |
gptkb:KLF10
|
| https://www.w3.org/2000/01/rdf-schema#label |
TIEG1
|
| gptkbp:locatedOnChromosome |
8q22.3
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
gptkb:bone fibrosis |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:proteinFamily |
zinc finger domain
|
| gptkbp:regulates |
gptkb:Wnt_signaling_pathway
bone metabolism cell cycle arrest osteoblast differentiation cellular differentiation cellular proliferation apoptotic pathways estrogen receptor signaling SMAD signaling insulin gene expression TGF-beta target genes p21 expression Bax expression Runx2 expression osteocalcin expression |
| gptkbp:UniProtID |
Q13118
|
| gptkbp:bfsParent |
gptkb:KLF10
|
| gptkbp:bfsLayer |
8
|