|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:KLF10
EGRalpha
TGF-beta-inducible early gene 1 protein
|
|
gptkbp:discoveredBy
|
Subramaniam et al.
|
|
gptkbp:discoveredIn
|
1995
|
|
gptkbp:encodedBy
|
KLF10 gene
|
|
gptkbp:Entrez_Gene_ID
|
7071
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:bone
gptkb:skeletal_muscle
gptkb:prostate
gptkb:testis
heart
liver
pancreas
|
|
gptkbp:family
|
gptkb:Kruppel-like_factor_family
|
|
gptkbp:fullName
|
Transforming growth factor-beta-inducible early growth response protein 1
|
|
gptkbp:function
|
gptkb:transcription_factor
regulates apoptosis
regulates cell growth
mediates TGF-beta signaling
|
|
gptkbp:gene
|
gptkb:KLF10
|
|
gptkbp:locatedOnChromosome
|
8q22.3
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:bone
fibrosis
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:proteinFamily
|
zinc finger domain
|
|
gptkbp:regulates
|
gptkb:Wnt_signaling_pathway
bone metabolism
cell cycle arrest
osteoblast differentiation
cellular differentiation
cellular proliferation
apoptotic pathways
estrogen receptor signaling
SMAD signaling
insulin gene expression
TGF-beta target genes
p21 expression
Bax expression
Runx2 expression
osteocalcin expression
|
|
gptkbp:UniProtID
|
Q13118
|
|
gptkbp:bfsParent
|
gptkb:KLF10
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TIEG1
|