|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:TRA
gptkb:TCRA@_gene
gptkb:T-cell_receptor_alpha_locus
|
|
gptkbp:associatedWith
|
gptkb:T-cell_acute_lymphoblastic_leukemia
|
|
gptkbp:component
|
gptkb:T-cell_receptor_complex
|
|
gptkbp:discoveredBy
|
Susumu Tonegawa (TCR discovery)
|
|
gptkbp:encodes
|
gptkb:T-cell_receptor_alpha_chain
|
|
gptkbp:Entrez_Gene_ID
|
6955
ENSG00000211785
|
|
gptkbp:expressedIn
|
T lymphocytes
|
|
gptkbp:fullName
|
gptkb:T_cell_receptor_alpha_locus
|
|
gptkbp:function
|
essential for adaptive immune response
involved in T-cell receptor formation
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:12156
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TCRA gene
|
|
gptkbp:involvedIn
|
gptkb:V(D)J_recombination
|
|
gptkbp:locatedOnChromosome
|
14
14q11.2
|
|
gptkbp:locusType
|
protein-coding
|
|
gptkbp:mutationAssociatedWith
|
immunodeficiency
|
|
gptkbp:numberOfExons
|
variable (due to V(D)J recombination)
|
|
gptkbp:OMIM
|
186880
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:pathway
|
gptkb:T_cell_receptor_signaling_pathway
gptkb:adaptive_immune_system
|
|
gptkbp:product
|
gptkb:T-cell_receptor_alpha_chain
|
|
gptkbp:symbol
|
gptkb:TRA
|
|
gptkbp:UniProtID
|
P01848
|
|
gptkbp:bfsParent
|
gptkb:alpha-beta_TCR
|
|
gptkbp:bfsLayer
|
7
|