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gptkbp:instanceOf
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gptkb:protein
|
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gptkbp:abbreviation
|
gptkb:TBP
|
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gptkbp:alternativeName
|
gptkb:TATA-binding_protein
gptkb:TATA_sequence-binding_protein
gptkb:TFIID_subunit_TBP
|
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gptkbp:binds
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gptkb:TATA_box
|
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gptkbp:component
|
gptkb:SL1
gptkb:TFIID
gptkb:TFIIIB
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gptkbp:conservedIn
|
archaea
eukaryotes
|
|
gptkbp:discoveredBy
|
gptkb:John_T._Kadonaga
gptkb:Robert_Tjian
|
|
gptkbp:discoveredIn
|
1989
|
|
gptkbp:encodedBy
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gptkb:TBP_gene
|
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gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000112592
|
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gptkbp:expressedIn
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gptkb:nucleus
|
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gptkbp:function
|
transcription initiation
|
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gptkbp:GO_term
|
GO:0003700
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TATA box binding protein
|
|
gptkbp:interactsWith
|
gptkb:TAFs
gptkb:RNA_polymerase_II
gptkb:TFIIA
gptkb:TFIIB
|
|
gptkbp:InterPro
|
IPR002870
|
|
gptkbp:length
|
339 amino acids (human)
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6q27_(human)
|
|
gptkbp:molecularWeight
|
~38 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:spinocerebellar_ataxia_17
intellectual disability
|
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gptkbp:OMIM
|
600075
|
|
gptkbp:organism
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
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gptkbp:orthologIn
|
gptkb:Saccharomyces_cerevisiae
gptkb:Caenorhabditis_elegans
gptkb:Drosophila_melanogaster
|
|
gptkbp:PDB
|
gptkb:1CDW
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
acetylation
|
|
gptkbp:proteinFamily
|
PF00352
|
|
gptkbp:RefSeq
|
gptkb:NM_003194
|
|
gptkbp:regulates
|
gene expression
|
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gptkbp:requires
|
RNA polymerase I transcription
RNA polymerase II transcription
RNA polymerase III transcription
basal transcription
|
|
gptkbp:structure
|
saddle-shaped
|
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gptkbp:UniProtID
|
gptkb:P20226
|
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gptkbp:bfsParent
|
gptkb:TBP
|
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gptkbp:bfsLayer
|
6
|