TATA sequence-binding protein

URI: https://gptkb.org/entity/TATA_sequence-binding_protein
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
transcription factor
gptkbp:alsoKnownAs gptkb:TBP
gptkbp:binds gptkb:TATA_box
gptkbp:component transcription factor IID (TFIID) complex
gptkbp:discoveredBy gptkb:Robert_Tjian
gptkbp:discoveredIn 1989
gptkbp:domain C-terminal core domain
N-terminal variable domain
gptkbp:encodedBy gptkb:TBP_gene
gptkbp:foundIn archaea
eukaryotes
gptkbp:function binds to TATA box in DNA
initiates transcription
gptkbp:GO GO:0003700
https://www.w3.org/2000/01/rdf-schema#label TATA sequence-binding protein
gptkbp:interactsWith gptkb:RNA_polymerase_II
general transcription factors
gptkbp:involvedIn gene expression regulation
preinitiation complex formation
gptkbp:locatedOnChromosome gptkb:chromosome_6_(human)
gptkbp:molecularWeight ~38 kDa
gptkbp:mutationAssociatedWith neurological disorders
spinocerebellar ataxia type 17
gptkbp:orthologIn gptkb:mouse
gptkb:yeast
gptkb:Drosophila_melanogaster
gptkbp:PDB gptkb:1CDW
gptkbp:requires transcription initiation
gptkbp:structure saddle-shaped
gptkbp:UniProtID gptkb:P20226
gptkbp:bfsParent gptkb:TATA_box_binding_protein
gptkbp:bfsLayer 7