|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activatedBy
|
cell proliferation
cytokine production
cytotoxic activity
|
|
gptkbp:alternativeName
|
gptkb:TCR
gptkb:T-lymphocyte_receptor
|
|
gptkbp:antigen
|
MHC-restricted
|
|
gptkbp:binds
|
gptkb:peptide-MHC_complex
|
|
gptkbp:composedOf
|
gptkb:CD3_complex
alpha chain
beta chain
|
|
gptkbp:database
|
gptkb:Gene_Ontology:GO:0042101
gptkb:UniProt:P01848
MeSH:D013601
|
|
gptkbp:discoveredBy
|
gptkb:James_P._Allison
|
|
gptkbp:domain
|
constant domain
variable domain
|
|
gptkbp:encodedBy
|
TCR genes
|
|
gptkbp:expressedIn
|
T cell development
surface of T lymphocytes
|
|
gptkbp:formsComplexWith
|
gptkb:CD3_proteins
|
|
gptkbp:foundIn
|
gptkb:T_cells
|
|
gptkbp:function
|
recognition of antigens
|
|
gptkbp:geneRearrangement
|
gptkb:V(D)J_recombination
|
|
gptkbp:hasEpitope
|
antigenic peptide
|
|
gptkbp:hasParatope
|
variable region
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
T-cell receptor (TCR)
|
|
gptkbp:involvedIn
|
adaptive immune response
|
|
gptkbp:ligand
|
gptkb:MHC_molecule
antigen peptide
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:mutationAssociatedWith
|
immunodeficiency
autoimmunity
|
|
gptkbp:relatedTo
|
B-cell receptor
|
|
gptkbp:requires
|
immune surveillance
T cell specificity
|
|
gptkbp:role
|
immunotherapy
autoimmune diseases
infectious disease response
cancer immunology
|
|
gptkbp:species
|
gptkb:human
gptkb:mouse
other vertebrates
|
|
gptkbp:structureType
|
heterodimer
|
|
gptkbp:studiedIn
|
immunology
|
|
gptkbp:subspecies
|
gptkb:alpha-beta_TCR
gptkb:gamma-delta_TCR
|
|
gptkbp:type
|
initiates T cell activation
|
|
gptkbp:bfsParent
|
gptkb:T-cells
|
|
gptkbp:bfsLayer
|
6
|