|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
Spleen tyrosine kinase beta
Sykb
|
|
gptkbp:biologicalProcess
|
gptkb:B_cell_receptor_signaling_pathway
immune response
protein tyrosine kinase activity
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:domain
|
kinase domain
SH2 domain
|
|
gptkbp:encodedBy
|
Syk gene (Mus musculus)
|
|
gptkbp:Entrez_Gene_ID
|
20963
|
|
gptkbp:enzymeCommissionNumber
|
EC 2.7.10.2
|
|
gptkbp:expressedIn
|
gptkb:B_lymphocytes
macrophages
hematopoietic cells
neutrophils
|
|
gptkbp:fullName
|
gptkb:Spleen_tyrosine_kinase
|
|
gptkbp:function
|
signal transduction
non-receptor tyrosine kinase
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Syk (Mus musculus)
|
|
gptkbp:interactsWith
|
gptkb:Vav1
gptkb:BLNK
gptkb:PLCĪ³2
|
|
gptkbp:length
|
635 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_13
|
|
gptkbp:molecularWeight
|
72 kDa
|
|
gptkbp:organism
|
gptkb:Mus_musculus
|
|
gptkbp:orthologIn
|
SYK (Homo sapiens)
|
|
gptkbp:PDB
|
gptkb:4PUZ
4FL2
4FL3
4FL4
4FL5
4FL6
4FL7
4FL8
4FL9
4FLA
4FLB
4FLC
4FLD
4FLE
4FLF
4FLG
4FLH
4FLI
4FLJ
4FLK
4FLL
4FLM
4FLN
4FLO
4FLP
4FLQ
4FLR
4FLS
4FLT
4FLU
4FLV
4FLW
4FLX
4FLY
4FLZ
|
|
gptkbp:phosphorylates
|
ITAM-containing receptors
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
|
gptkbp:refseqProtein
|
NP_035591.2
|
|
gptkbp:UniProtID
|
gptkb:P43405
|
|
gptkbp:bfsParent
|
gptkb:Syk
|
|
gptkbp:bfsLayer
|
8
|