Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
gptkb:SNA
gptkb:SNAI1 gptkb:SNAIL |
| gptkbp:associatedWith |
cancer progression
fibrosis |
| gptkbp:encodes |
gptkb:Snail_family_transcriptional_repressor_1
|
| gptkbp:Entrez_Gene_ID |
6615
|
| gptkbp:function |
transcriptional repressor
|
| gptkbp:HGNC_ID |
HGNC:11129
|
| https://www.w3.org/2000/01/rdf-schema#label |
Snai1
|
| gptkbp:involvedIn |
epithelial-mesenchymal transition
|
| gptkbp:locatedOnChromosome |
gptkb:20q13.2
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
gptkb:Danio_rerio
gptkb:Gallus_gallus gptkb:Mus_musculus |
| gptkbp:protein_structure |
contains C2H2-type zinc fingers
|
| gptkbp:proteinFamily |
zinc finger transcription factors
|
| gptkbp:regulates |
gptkb:Wnt_signaling
gptkb:Hedgehog_signaling apoptosis cell differentiation cell survival angiogenesis cell migration immune response cell cycle DNA damage response cell polarity cell adhesion p53 pathway tumor metastasis TGF-beta signaling extracellular matrix remodeling MAPK signaling NF-kB signaling Notch signaling PI3K/AKT signaling cell invasion neural crest formation fibroblast activation mesoderm formation stem cell properties E-cadherin expression EMT in cancer EMT in development |
| gptkbp:transcription_factor_binding_site |
gptkb:E-box
|
| gptkbp:UniProtID |
gptkb:O95863
|
| gptkbp:bfsParent |
gptkb:SNAI1
|
| gptkbp:bfsLayer |
7
|